Here's a weed that's easy to pull and one where you might feel that an investment of time now will have a real preventive impact. The weed is Euphorbia terracina (Geraldton carnation weed, false caper), and it's just getting established nearby. Early prevention could make a difference, so exterminate on sight.
Pulled by the roots. There is an irritating milky sap that is best avoided by using gloves.